Pages tagged "cancer"

  • Allele Biotech Takes Major Step into Nano Antibody Leadership Position

    Posted on News From Our Members by · August 28, 2015 10:10 PM

    August 26, 2015 07:57 AM Eastern Daylight Time

    SAN DIEGO--(BUSINESS WIRE)--Allele Biotechnology & Pharmaceuticals Inc., a San Diego based life sciences company with a focus on novel technology development, releases the first group of a brand new class of antibodies against crucial biological targets to the research market. This week, Allele launches nano-antibodies isolated from llamas against human bFGF, P16, VEGF, and TNFa, which are all important targets in the field of cancer biology.

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  • Orphagen Awarded SBIR Grant

    Posted on News From Our Members by · August 28, 2015 9:29 PM

    July 1, 2015. Orphagen Pharmaceuticals announced today that the National Institutes of Health (NIH) National Cancer Institute (NCI) has awarded the company $224,954 under the Small Business Innovative Research (SBIR) program to identify small molecule antagonist ligands for an novel drug discovery target for cancer immunotherapy. Orphagen proposes to find drug-like molecules to a previously unexplored orphan drug target that normally suppresses the immune response.

     “We believe there is an opportunity to identify small molecule ligands to this orphan drug target.  The ligands will enhance T cell activation and thus stimulate anti-tumor responses by enhancing the ongoing immune surveillance that already occurs in cancer patients.” said Dr. Haiyan Tao, Scientist and Principal Investigator of the grant. The drug-like molecules identified from this project would create a powerful and potentially safer therapeutic tool to enhance clinical cancer immunotherapy and improve patient survival.

    Orphagen is a first-mover in the identification of small molecule compounds to three orphan nuclear receptors. Support from the NIH is a critical part of the Company’s overall strategy to discover new classes of drugs and commercialize them through partnerships.

  • Crinetics Pharmaceuticals Awarded $1.5MM NIH Phase II SBIR Grant for PCOS Research

    Posted on News From Our Members by · February 15, 2015 6:00 PM

    Crinetics Pharmaceuticals receives a $1.5MM Phase II SBIR grant to develop orally-available, small molecule kisspeptin receptor antagonists to treat polycystic ovary syndrome (PCOS) and other women’s health disorders.

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