Welcome to SDEE

Welcome to San Diego Entrepreneurs Exchange! 

The San Diego Entrepreneurs Exchange (SDEE) is a nonprofit 501(c)(3) organization run by local entrepreneurs for entrepreneurs and pre-entrepreneurs interested in Life Sciences, Biotech, Pharma, Medical Devices, Tech and Alternative Energy. SDEE was founded to provide a voice and resources for early stage startups, to encourage new entrepreneurs, and sponsor networking and educational services to help develop skills necessary to bring new businesses and funding to the San Diego area. 

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  • Thursday, January 19, 2017 at 05:00 PM · 15 rsvps
    New English Brewing Company in San Diego, CA

    January Happy Hour

    Come network with your fellow San Diego entrepreneurs at Happy Hour hosted by New English Brewing Company.

    Everyone is welcome (registration is free so please RSVP!), SDEE members get 10% drinks discount. Addicted To Flavor Mexican food will be serving.

    Thursday, February 16, 2017 at 05:00 PM
    New English Brewing Company in San Diego, CA

    February Happy Hour

    Come network with your fellow San Diego entrepreneurs at Happy Hour hosted by New English Brewing Company.

    Everyone is welcome (registration is free!), SDEE members get 10% drinks discount.

    Thursday, February 23, 2017 at 05:30 PM · $30.00 USD · 2 rsvps
    Hera Hub in San Diego, CA

    WORKSHOP: Intellectual Property for Entrepreneurs: Simple Principles for Navigating a Complex Field

    Intellectual property is essential for the success and growth of startups- whether through funding, partnerships, mergers, or product sales. Navigating through the intricacies of IP to avoid pitfalls and gain a working knowledge is critical for start up executives.

    Join us for an engaging and informative workshop where our panel of experts will provide practical advice and insight on several topics, including:

    • Basics of copyrights, trademarks, patents
    • Business strategy/ patent strategy
    • Types of patents
    • When, where & how to file
    • Cost of filing & prosecuting
    • Pitfalls of not filing
    • Litigation and how to avoid it
    • Ownership/Inventorship
    • IP Audits
    • Patent searches - when and how to search

     Speakers:

     Liz Bui, Vice President and IP Counsel, ViaCyte, Inc.

     Eric Hanscom, Partner, Hanscom, Alexeev, McDaniel, LLP

     Neil Thompson, Patent Agent

    Thursday, March 16, 2017 at 05:00 PM
    New English Brewing Company in San Diego, CA

    March Happy Hour

    Come network with your fellow San Diego entrepreneurs at Happy Hour hosted by New English Brewing Company.

    Everyone is welcome (registration is free!), SDEE members get 10% drinks discount.


  • News From SDEE Members

    Alzheimer's Disease Year-in-Review 2016

    Journey with me through this mini and wholly incomplete Alzheimer's disease 2016 year-in-review. For the full post on LinkedIn, please see: http://tinyurl.com/hx28m3j
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    Does the 505(b)(2) Regulatory Pathway for NDA's Provide an Adequate ROI?

    I have a post on LinkedIn where I share a few thoughts about the benefits and limitations of developing drugs using the 505(b)(2) regulatory pathway. Hardly a week goes by without a pharmaceutical company expressing the desire to reap the benefits of developing a drug using the “505(b)(2) regulatory pathway”. What are 505(b)(2) new drug applications (NDAs) and do they really provide a meaningful advantage to pharmaceutical companies? For the full post on LinkedIn, please see: http://tinyurl.com/j9fh2zn  
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  • Meet SDEE Community

    Happy New Year from SDEE!

    Wishing you a happy and successful 2017! Thank you to our members, sponsors and volunteers for helping us provide educational & networking entrepreneur events to the San Diego community. Check out the highlights from 2016 in our newsletter http://www.sdentrepreneurs.org/newsletters. Have an idea for an event or workshop you would like next year? We'd love to hear about it. Just contact Danielle Hayes at dhayes@sdentrepreneurs.org.    
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    International Federation for Adipose Therapeutics and Science

    International Federation for Adipose Therapeutics and Science 2016 Conference Highlights by Neil Thompson Fat to the face: My time at IFATS 2016 Why would you want to put fat in your face? That’s the question I asked myself before attending the International Federation for Adipose Therapeutics and Science (IFATS) 2016 annual meeting. I don’t know too much about fat except that most of us would rather have less of it.  Held from November 17-20, clinicians, researchers, and industry folk all gathered in San Diego at the Westin San Diego Gaslamp Quarter. I was among them, and I was excited to be there. For decades, most cosmetic surgeries were carried out with non-biological fillers. Plump up your face? Eliminate dimples on your thigh? Fillers fit the bill. The problem with them? They don’t stick around. Up to 60% of volume is lost with these types of fillers. Fat became the solution. In fat, more and more study has focused on using fat from liposuction to address filling those problem areas. The fatty material removed from the body during liposuction, called lipoaspirate, was historically seen as waste and thrown away. No more. Surgeons are now separating the fat tissue from lipoaspirate through various means, like centrifugation and simple decanting, to access the stem cells residing in the tissue. Stem cells have the ability to transform, given the correct cues, into fat cells. The stem cells can then be reinjected into problem areas so that the stem cells attract cytokines that turn the stem cells into fat cells. Many companies, some of which were exhibitors at the meeting, are working on methods to better separate the fat tissue from lipoaspirate while increasing the yield and viability of the isolated stem cells. Results are promising. Companies like Tissue Genesis and LifeCell are developing these fat-isolating technologies. LifeCell in particular has launched a product, the REVOLVE™ System, which looks like a salad spinner. It operates by gently spinning around lipoaspirate to separate the fat tissue from blood cells, debris, and extraneous fluid. The entire process takes about 90 minutes and produces more viable stem cells than decanting alone. Another company, Andrews Technologies, showcased HydraSolve®, which uses a specially made cannula to liquefy fat with warm pressurized saline. Fat sucked into the cannula comes in contact with warm saline circulating within the cannula, which liquefies the fat. The cell viability within the aspirated fat is higher than in other traditional fat harvesting techniques.  Want to avoid liposuction and only want to fix a tiny problem area? MTF has a product, Renuva™, which can do just that. Made of allograft fat tissue (i.e. other people’s fat), Renuva is an injectable off the shelf product, eliminating the need for fat harvesting by liposuction. A competitor product, Allofill™ by Biologica Technologies, also exhibited at the meeting. In addition to companies showing their wares, researchers also presented their work. Ever heard of microneedling? Me neither. The microneedler looks like a small rolling pin with tiny needles protruding from it. Researchers from Turkey’s Koc University School of Medicine found that rolling the microneedler over the problem area prior to fat injection increased vascularity and led to quicker engraftment of the injected fat. Oxysterol was a new term for me, too. A derivative of cholesterol, researchers at UCLA showed a link between oxysterol treatment and decrease in weight. They are looking into developing oxysterol treatments to prevent obesity. Research out of the University of Louisville is experimenting with developing cell-encapsulating spheroids. The team is 3D printing hydrophilic dots onto hydrophobic surfaces to create the spheroids. A 3D morphology of the cell-binding surface has been shown to be quite influential in maintaining the in vivo characteristics of cells. Cells plated on a flat surface typically don’t behave like cells found in the body. The major takeaway from the meeting is that there’s no gold standard for isolating fat from lipoaspirate. Some swear by liposuction followed by allowing the fat layer to separate from the blood cell-laden liquid. Others advocate for gently spinning or centrifuging the lipoaspirate. In the next few years, I suspect more study will reveal the optimal method to get at the fat tissue’s stem cells and that method will be widely adopted. Barring prohibitive costs, of course. So why would you want to put fat in your face? Because it works! Besides, we put Botox in our faces. Why not add some fat to the mix?    
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SDEE is a nonprofit 501(c)(3) organization founded by local San Diego entrepreneurs
in order to provide a voice for the early stage start-up, to support new entrepreneurs and their companies,
and to sponsor networking and educational events
to help develop the skills necessary to bring funding, business, and jobs to the San Diego area.

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